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Can boosting hemoglobin help kidney transplant patients feel better and protect their kidneys?

NCT ID NCT00396435

Completed Disease control Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether raising hemoglobin levels with a drug called epoetin (Neorecormon) could improve quality of life and slow kidney function decline in people who had a kidney transplant and now have chronic graft dysfunction. About 128 adults who had a transplant 1 to 20 years ago and had reduced kidney function took part. They were split into two groups: one aimed for a higher hemoglobin target, the other for a lower one. The study measured quality of life after 6 months and kidney function over 24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Epoetin (Neorecormon)
What this could lead to
If successful, this could show that managing anemia with epoetin improves daily well-being and helps preserve kidney function in transplant patients.
What could go wrong
This is a completed Phase 4 trial with 128 participants, so results are limited in scope. The intervention may not significantly slow kidney decline or improve quality of life for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anemia chronic transplant rejection kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAEMIA KIDNEY FAILURE RENAL TRANSPLANTATION

Contacts and locations

Locations

  • CHU Clermont Ferrand - Hôpital Gabriel Monpied

    Clermont-Ferrand, 63003, France

  • CHU de Tours - Hôpital Bretonneau

    Tours, 37044, France

  • Hôpital Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • Hôpital Calmette

    Lille, 59037, France

  • Hôpital Civil

    Strasbourg, 67091, France

  • Hôpital Clémenceau

    Caen, 14033, France

  • Hôpital Dupuytren

    Limoges, 87052, France

  • Hôpital Foch

    Suresnes, 92151, France

  • Hôpital Henri Mondor

    Créteil, 94010, France

  • Hôpital Maison Blanche

    Reims, 51092, France

  • Hôpital Necker - Enfants Malades

    Paris, 75743, France

  • Hôpital Pasteur

    Nice, 06002, France

  • Hôpital Pellegrin

    Bordeaux, 33076, France

  • Hôpital Pontchaillou

    Rennes, 35033, France

  • Hôpital Rangueil

    Toulouse, 33076, France

  • Hôpital Sud

    Amiens, 80000, France

  • Hôpital de Bois Guillaume

    Bois-Guillaume, 76230, France

  • Hôpital de la Conception

    Marseille, 13385, France

  • Hôpital de la Milétrie

    Poitiers, 86021, France

  • Hôpital de la Tronche

    Grenoble, 38043, France

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