New drug aims to slow rare heart disease by targeting toxic proteins
NCT ID NCT06194825
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 26 times
Summary
This study tests an investigational drug called eplontersen in 64 Chinese adults with transthyretin amyloid cardiomyopathy, a condition where abnormal proteins build up in the heart. The goal is to see if eplontersen can safely lower those protein levels compared to a placebo over 24 weeks, followed by an 80-week open-label phase. Participants must be 20-90 years old and not pregnant.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research Site
Beijing, 100029, China
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Research Site
Beijing, 100034, China
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Research Site
Beijing, 100037, China
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Research Site
Beijing, 100191, China
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Research Site
Beijing, 100730, China
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Research Site
Changsha, 410008, China
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Research Site
Changsha, 410013, China
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Research Site
Changsha, 430033, China
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Research Site
Chengdu, 610041, China
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Research Site
Chengdu, 610072, China
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Research Site
Chongqing, 400010, China
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Research Site
Chongqing, 400042, China
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Research Site
Guangzhou, 510062, China
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Research Site
Guangzhou, 510100, China
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Research Site
Hangzhou, 310003, China
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Research Site
Hangzhou, 310014, China
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Research Site
Hangzhou, 310052, China
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Research Site
Ha’erbin, 150001, China
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Research Site
Jinan, 250001, China
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Research Site
Nanchang, 330006, China
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Research Site
Shanghai, 200032, China
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Research Site
Suzhou, 215006, China
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Research Site
Taiyuan, 030001, China
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Research Site
Wuhan, 430030, China
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Research Site
Wuhan, 430060, China
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Research Site
Xi'an, 710061, China
Conditions
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