TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
Clinical trials for TRANSTHYRETIN AMYLOID CARDIOMYOPATHY explained in plain language.
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New drug may boost protein levels in heart disease patients
Disease control Recruiting nowThis study tests whether switching from tafamidis to acoramidis can raise blood levels of transthyretin (TTR) in adults with transthyretin amyloid cardiomyopathy (ATTR-CM). The drug acoramidis stabilizes TTR to prevent harmful amyloid clumps that stiffen the heart. Researchers wi…
Matched conditions: TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
Phase: PHASE4 • Sponsor: Bayer • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New drug aims to scrub sticky proteins from heart muscle
Disease control Recruiting nowThis early study tests a drug called coramitug in 14 people with ATTR-CM, a heart condition caused by abnormal protein buildup. The drug is designed to bind to and help remove these protein clumps from the heart. Researchers will use special scans to see where the drug goes and w…
Matched conditions: TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
Phase: PHASE1 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New scan could spot hidden amyloid in heart and organs
Diagnosis Recruiting nowThis study tests a radioactive imaging agent called Iodine-124 evuzumitide (AT-01) in 150 people with systemic amyloidosis. The goal is to see how well it detects amyloid deposits in the heart and other organs using PET/MRI or PET/CT scans. If accurate, it could become a new tool…
Matched conditions: TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
Phase: PHASE2 • Sponsor: Oregon Health and Science University • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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Could a simple scan unlock better heart treatment?
Knowledge-focused Recruiting nowThis study tests a new PET scan technique to better track heart damage in people with a condition called ATTR-CM, a progressive heart muscle disease. Researchers will scan 140 participants to see if the imaging can show how well treatments are working. The goal is to improve moni…
Matched conditions: TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC