Custom knee implant tested for Long-Term relief
NCT ID NCT03755388
First seen Mar 11, 2026 · Last updated Jun 23, 2026 · Updated 11 times
Summary
This study is testing a custom-made metal knee implant called Episealer for people with cartilage damage in the knee. The implant is designed based on each patient's MRI scan. Researchers are following a small group of patients for up to 10 years to see if the implant stays in place and helps with pain and function.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UZ Leuven
Leuven, Vlaams-Brabant, 3000, Belgium
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Episealer device (custom metal implant for knee cartilage)
What this could lead to
If successful, this could offer a long-lasting option for people with knee cartilage damage who haven't been helped by other surgeries.
What could go wrong
This is a very small, early-stage trial with only 4 participants, so results may not apply to everyone. The implant could fail or require removal over time.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.