Surgery before IVF may boost pregnancy odds in deep endometriosis

NCT ID NCT02948972

Recruiting now Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether surgically removing deep endometriosis from the bowel before IVF improves pregnancy rates compared to IVF alone. It includes 120 women with infertility and pain from deep endometriosis. Participants are randomly assigned to either have surgery then IVF, or IVF without surgery. The main goal is to see who gets a clinical pregnancy after two IVF cycles.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: complete surgery of colorectal deep infiltrating endometriosis
What this could lead to: If it works, this could show that surgery before IVF increases the chance of pregnancy for women with deep endometriosis and infertility.
What could go wrong: This is a relatively small trial (120 people) and surgery carries risks like infection or bowel injury. The benefit over IVF alone is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL DEEP INFILTRATING ENDOMETRIOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endometriosis endometriosis of intestine infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS INFERTILITY

Contacts and locations

Locations

AP-HP, Hôpital Tenon
RECRUITING

Paris, France
CHU
RECRUITING

Clermont-Ferrand, France
CHU
RECRUITING

Poissy, France
CHU
RECRUITING

Rouen, France
Hôpital Jeanne de Flandres, CHRU
RECRUITING

Lille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.