Surgery before IVF may boost pregnancy odds in deep endometriosis
NCT ID NCT02948972
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether surgically removing deep endometriosis from the bowel before IVF improves pregnancy rates compared to IVF alone. It includes 120 women with infertility and pain from deep endometriosis. Participants are randomly assigned to either have surgery then IVF, or IVF without surgery. The main goal is to see who gets a clinical pregnancy after two IVF cycles.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
complete surgery of colorectal deep infiltrating endometriosis
What this could lead to
If it works, this could show that surgery before IVF increases the chance of pregnancy for women with deep endometriosis and infertility.
What could go wrong
This is a relatively small trial (120 people) and surgery carries risks like infection or bowel injury. The benefit over IVF alone is not yet proven.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP-HP, Hôpital Tenon
RECRUITINGParis, France
Contact
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CHU
RECRUITINGClermont-Ferrand, France
Contact
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CHU
RECRUITINGPoissy, France
Contact
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CHU
RECRUITINGRouen, France
Contact
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Hôpital Jeanne de Flandres, CHRU
RECRUITINGLille, France
Contact