Could a diabetes pill protect kids' kidneys? new trial launches

NCT ID NCT07107945

Recruiting now Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 5 times

Summary

This study tests whether empagliflozin, a medicine already used for diabetes, can help children aged 2 to 17 with chronic kidney disease. About 120 kids will take either the drug or a placebo for 6 months, then everyone gets the drug for a year. Researchers will check kidney function and safety through regular visits and tests.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASE

Contacts and locations

Locations

Alder Hey Children's Hospital
RECRUITING

Liverpool, L12 2AP, United Kingdom
Amsterdam University Medical Center
RECRUITING

Amsterdam, 1105 AZ, Netherlands
Ankara Universitesi Tip Fakultesi
RECRUITING

Ankara, 06620, Turkey (Türkiye)
Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITING

Chicago, Illinois, 60611, United States
Azienda Ospedaliera Universitaria di Padova
RECRUITING

Padova, 35128, Italy
BC Children's Hospital
RECRUITING

Vancouver, British Columbia, V6H 3N1, Canada
Birmingham Children's Hospital
RECRUITING

Birmingham, B4 6NH, United Kingdom
Boston Children's Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States
Bristol Royal Hospital for Children
RECRUITING

Bristol, BS2 8BJ, United Kingdom
CHC Mont Légia
RECRUITING

Liège, 4000, Belgium
CHUC - Centro Hospitalar e Universitario de Coimbra, EPE
RECRUITING

Coimbra, 3000-602, Portugal
CHUP, EPE - Centro Materno Infantil do Norte
RECRUITING

Porto, 4050-651, Portugal
Children's Hospital of Michigan
NOT_YET_RECRUITING

Detroit, Michigan, 48201, United States
Children's Hospital of Philadelphia
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Children's Mercy Hospitals and Clinics
RECRUITING

Kansas City, Missouri, 64108, United States
Chonnam National University Hospital
RECRUITING

Gwangju, 61469, South Korea
Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Cliniques Universitaires Saint-Luc
RECRUITING

Brussels, 1200, Belgium
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Equipo Ciencia
RECRUITING

CABA, C1428BNF, Argentina
Erasmus Medisch Centrum
RECRUITING

Rotterdam, 3015 GD, Netherlands
Fondazione IRCCS Ca'Granda-Ospedale Maggiore Policlinico
RECRUITING

Milan, 20122, Italy
Great North Children's Hospital
RECRUITING

Newcastle upon Tyne, NE1 4LP, United Kingdom
Great Ormond Street Hospital
RECRUITING

London, WC1N 3JH, United Kingdom
HOP Armand-Trousseau
RECRUITING

Paris, 75012, France
HOP Enfants et Adolescents
RECRUITING

Nantes, 44093, France
HOP Timone
RECRUITING

Marseille, 13005, France
HOP des Enfants
RECRUITING

Toulouse, 31059, France
HUB CHU Brugmann
RECRUITING

Brussels, 1020, Belgium
Hacettepe University
RECRUITING

Ankara, 06230, Turkey (Türkiye)
Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Hopital Necker
RECRUITING

Paris, 75015, France
Hospital Italiano de Buenos Aires
RECRUITING

CABA, C1199ABB, Argentina
Hospital Regional Universitario de Málaga
RECRUITING

Málaga, 29011, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario de Cruces
RECRUITING

Bilbao, 48903, Spain
Hospital Virgen del Rocío
RECRUITING

Seville, 41013, Spain
Hospital de Niños Dr. Ricardo Gutierrez
NOT_YET_RECRUITING

CABA, C1425EFD, Argentina
Hôpital Louis Pradel
RECRUITING

Bron, 69500, France
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Istanbul Capa University
RECRUITING

Istanbul, 34093, Turkey (Türkiye)
Istituto G. Gaslini
RECRUITING

Genova, 16147, Italy
Jersey Shore University Medical Center
NOT_YET_RECRUITING

Neptune City, New Jersey, 07753, United States
Jim Pattison Children's Hospital
RECRUITING

Saskatoon, Saskatchewan, S7N 0W8, Canada
Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
KK Women's and Children's Hospital
RECRUITING

Singapore, 229899, Singapore
Karolinska University Hospital
RECRUITING

Stockholm, 141 86, Sweden
Kyungpook National University Hospital
RECRUITING

Daegu, 41944, South Korea
M Health Fairview Masonic Children's Hospital
RECRUITING

Minneapolis, Minnesota, 55454, United States
McGill University Health Centre (MUHC)
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Monash Children's Hospital
RECRUITING

Clayton, Victoria, 3168, Australia
NIHR Southampton Clinical Research Facility
RECRUITING

Southampton, SO16 6YD, United Kingdom
National University Hospital
RECRUITING

Singapore, 119074, Singapore
Nationwide Children's Hospital
NOT_YET_RECRUITING

Columbus, Ohio, 43205, United States
Nottingham Children's Hospital
RECRUITING

Nottingham, NG7 2UH, United Kingdom
Novak Center for Children's Health
RECRUITING

Louisville, Kentucky, 40202, United States
Osmangazi University
RECRUITING

Odunpazari, 26040, Turkey (Türkiye)
Ospedale Pediatrico Bambino Gesù
RECRUITING

Roma, 00165, Italy
Phoenix Children's Hospital
NOT_YET_RECRUITING

Phoenix, Arizona, 85016, United States
Primary Children's Hospital
RECRUITING

Salt Lake City, Utah, 84113, United States
Queen Elizabeth University Hospital
RECRUITING

Glasgow, G51 4TF, United Kingdom
Queensland Children's Hospital
RECRUITING

South Brisbane, Queensland, 4101, Australia
Radboud Universitair Medisch Centrum
RECRUITING

Nijmegen, 6525 GA, Netherlands
Sahlgrenska Universitetssjukhuset, Östra
RECRUITING

Gothenburg, 416 85, Sweden
Seattle Children's Hospital
RECRUITING

Seattle, Washington, 98105, United States
Semmelweis University, Faculty of Medicine
RECRUITING

Budapest, 1083, Hungary
Seoul National University Bundang Hospital
RECRUITING

Seongnam, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Stanford University School of Medicine
RECRUITING

Palo Alto, California, 94304, United States
The Children's Hospital at Westmead
RECRUITING

Westmead, New South Wales, 2145, Australia
The Children's Memorial Health Institute
RECRUITING

Warsaw, 04730, Poland
The Hospital for Sick Children
NOT_YET_RECRUITING

Toronto, Ontario, M5G 1X8, Canada
The Royal Children's Hospital
RECRUITING

Parkville, Victoria, 3052, Australia
ULS de Santa Maria, E.P.E
NOT_YET_RECRUITING

Lisbon, 1600-190, Portugal
ULS de São José, E.P.E. - Hospital Dona Estefânia
RECRUITING

Lisbon, 1169-045, Portugal
UMC Utrecht
RECRUITING

Utrecht, 3584 CX, Netherlands
UZ Leuven
RECRUITING

Leuven, 3000, Belgium
Universitair Medisch Centrum Groningen
RECRUITING

Groningen, 9713 GZ, Netherlands
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium
University Children's Hospital in Lublin
NOT_YET_RECRUITING

Lublin, 20-093, Poland
University Clinical Hospital in Wrocław
NOT_YET_RECRUITING

Wroclaw, 50 556, Poland
University of Alabama at Birmingham
NOT_YET_RECRUITING

Birmingham, Alabama, 35233, United States
University of Alberta Hospital (University of Alberta)
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
University of California Davis
RECRUITING

Sacramento, California, 95817, United States
University of California Los Angeles
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
University of California San Francisco
NOT_YET_RECRUITING

San Francisco, California, 94158, United States
University of Debrecen Clinical Centre
RECRUITING

Debrecen, 4032, Hungary
University of Miami
NOT_YET_RECRUITING

Miami, Florida, 33136, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of New Mexico
RECRUITING

Albuquerque, New Mexico, 87131, United States
University of Pecs
RECRUITING

Pécs, 7623, Hungary
University of Texas Southwestern Medical Center
NOT_YET_RECRUITING

Dallas, Texas, 75235, United States
University of Wisconsin
NOT_YET_RECRUITING

Madison, Wisconsin, 53705-9123, United States
Universitätsklinikum Hamburg, Eppendorf
RECRUITING

Hamburg, 20246, Germany
Universitätsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
Universitätsklinikum Köln (AöR)
RECRUITING

Cologne, 50937, Germany
Universitätsklinikum Tübingen
RECRUITING

Tübingen, 72076, Germany
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-211, Poland
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Virginia Commonwealth University Health Systems
RECRUITING

Richmond, Virginia, 23219, United States
Wojewodzki Szpital Zespolony Im.L.Rydygiera W Toruniu
RECRUITING

Torun, 87-100, Poland

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