Can a loved One's voice help predict brain recovery?

NCT ID NCT05740735

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study explores whether using emotional sounds—like a patient's own name spoken by a family member—can improve brain wave tests that help predict recovery in people with disorders of consciousness. Researchers will compare brain responses to familiar versus unfamiliar voices in 114 ICU patients after cardiac arrest, stroke, or head injury. The goal is to see if emotional sounds provide a more reliable prognosis than standard neutral sounds.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: emotional sounds (own name spoken by a familiar voice)
What this could lead to: If successful, this could lead to a more reliable way to predict recovery in patients with disorders of consciousness, helping families and doctors make better decisions.
What could go wrong: This is an early-stage study with only 114 participants, so results may not apply to all patients. The approach is experimental and may not improve prognosis accuracy.

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Conditions

The condition(s) this trial relates to.

cardiac arrest Coma Consciousness Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISORDER OF CONSCIOUSNESS

Contacts and locations

Locations

Medical ICU, Cochin Hospital, APHP.Centre
RECRUITING

Paris, Île-de-France Region, 75014, France
Medical ICU, HEGP Hospital, APHP.Centre
NOT_YET_RECRUITING

Paris, IDF, 75015, France

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