Can a higher radiation dose help older brain cancer patients live longer?
NCT ID NCT06835803
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether a higher daily dose of radiation over three weeks is better than the standard dose for people aged 65 and older with newly diagnosed glioblastoma, an aggressive brain cancer. About 56 participants will be randomly assigned to one of two radiation schedules. The study will compare survival, tumor control, side effects, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy
What this could lead to
If successful, this could show that a higher daily radiation dose over three weeks improves survival and tumor control for older adults with glioblastoma.
What could go wrong
This is a small early-phase trial (56 participants) and may not prove effective. Higher radiation doses could also increase side effects like brain swelling or fatigue.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Brigham Cancer Center, Milford Hospital
RECRUITINGMilford, Massachusetts, 01757, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Brigham Cancer Center, South Shore Hospital
RECRUITINGSouth Weymouth, Massachusetts, 02190, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••