New drug aims to stop liver damage in MASH patients

NCT ID NCT07221188

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tests a new medicine called efimosfermin alfa in people with MASH, a liver disease linked to metabolic issues. The goal is to see if the drug is safe and tolerable for patients with moderate liver scarring (stage F2 or F3). About 1,250 adults will receive either the drug or a placebo, and researchers will monitor side effects and lab changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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Locations

  • GSK Investigational Site

    RECRUITING

    Arcadia, California, 91006, United States

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  • GSK Investigational Site

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    Covina, California, 91723, United States

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  • GSK Investigational Site

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    Los Angeles, California, 90057, United States

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  • GSK Investigational Site

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    Santa Maria, California, 93458, United States

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  • GSK Investigational Site

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    Cape Coral, Florida, 33914, United States

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  • GSK Investigational Site

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    Doral, Florida, 33016, United States

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  • GSK Investigational Site

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    Hialeah, Florida, 33016, United States

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  • GSK Investigational Site

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    Inverness, Florida, 34452, United States

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  • GSK Investigational Site

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    Jacksonville, Florida, 32216, United States

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  • GSK Investigational Site

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    Kissimmee, Florida, 34744, United States

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  • GSK Investigational Site

    RECRUITING

    Lakeland, Florida, 33803, United States

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  • GSK Investigational Site

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    Maitland, Florida, 32751, United States

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  • GSK Investigational Site

    RECRUITING

    Miami, Florida, 33135, United States

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  • GSK Investigational Site

    RECRUITING

    Miami, Florida, 33155, United States

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  • GSK Investigational Site

    RECRUITING

    Miami, Florida, 33156, United States

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  • GSK Investigational Site

    RECRUITING

    Miami, Florida, 33184, United States

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  • GSK Investigational Site

    RECRUITING

    Miami Lakes, Florida, 33014, United States

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  • GSK Investigational Site

    RECRUITING

    Ocala, Florida, 34471, United States

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  • GSK Investigational Site

    RECRUITING

    Palmetto Bay, Florida, 33157, United States

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  • GSK Investigational Site

    RECRUITING

    Topeka, Kansas, 66606, United States

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  • GSK Investigational Site

    RECRUITING

    Springfield, Missouri, 62703, United States

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  • GSK Investigational Site

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    St Louis, Missouri, 63141, United States

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  • GSK Investigational Site

    RECRUITING

    Jersey City, New Jersey, 07059, United States

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  • GSK Investigational Site

    RECRUITING

    East Syracuse, New York, 13057, United States

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  • GSK Investigational Site

    RECRUITING

    New York, New York, 10036, United States

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  • GSK Investigational Site

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    Morehead City, North Carolina, 28557, United States

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  • GSK Investigational Site

    RECRUITING

    Akron, Ohio, 44320, United States

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  • GSK Investigational Site

    RECRUITING

    Springboro, Ohio, 45066, United States

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  • GSK Investigational Site

    RECRUITING

    Austin, Texas, 78745, United States

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  • GSK Investigational Site

    RECRUITING

    Austin, Texas, 78759, United States

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  • GSK Investigational Site

    RECRUITING

    Brownsville, Texas, 78526, United States

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  • GSK Investigational Site

    RECRUITING

    Dallas, Texas, 75243, United States

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  • GSK Investigational Site

    RECRUITING

    DeSoto, Texas, 75115, United States

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  • GSK Investigational Site

    RECRUITING

    Richmond, Texas, 77406, United States

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  • GSK Investigational Site

    RECRUITING

    San Antonio, Texas, 78215, United States

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  • GSK Investigational Site

    RECRUITING

    San Antonio, Texas, 78229, United States

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  • GSK Investigational Site

    RECRUITING

    Seabrook, Texas, 77586, United States

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  • GSK Investigational Site

    RECRUITING

    Tomball, Texas, 77375, United States

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  • GSK Investigational Site

    RECRUITING

    Waco, Texas, 76710, United States

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  • GSK Investigational Site

    RECRUITING

    Waco, Texas, 76712, United States

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  • GSK Investigational Site

    RECRUITING

    West Jordan, Utah, 84088, United States

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  • GSK Investigational Site

    RECRUITING

    Manassas, Virginia, 20110, United States

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  • GSK Investigational Site

    RECRUITING

    Seattle, Washington, 98105, United States

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Conditions

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