ECMO kidney care: one line or two?

NCT ID NCT06038162

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two methods for providing kidney dialysis to patients on ECMO (a heart-lung machine). One method uses a separate line for dialysis, while the other connects the dialysis machine directly into the ECMO circuit. The goal is to see if the direct connection works just as well, possibly reducing infections and bleeding. About 158 adults on ECMO who need kidney therapy will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If this trial succeeds, it could show that connecting kidney therapy directly into the ECMO circuit is just as effective as using a separate line, potentially reducing complications.
What could go wrong
This is a relatively small, early-stage trial focused on equipment performance, not a new drug or cure. The results may not change practice if the integrated method causes safety issues like air bubbles or clotting.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHP, Institut de Cardiologie, Service d'anesthésie-réanimation cardiovasculaire, Hôpital de la Pitié-Salpêtrière

    RECRUITING

    Paris, France

  • APHP, Institut de cardiologie, Service de Médecine Intensive Réanimation, Hôpital Pitié-Salpêtrière

    RECRUITING

    Paris, France

  • CHU de Bordeaux, GH Sud, Service d'anesthésie-réanimation cardiovasculaire, Hôpital cardiologique

    RECRUITING

    Bordeaux, France

  • CHU de Clermont Ferrand, Pôle de médecine péri-opératoire/Chirurgie cardiaque, Hôpital Gabriel Montpied

    RECRUITING

    Clermont-Ferrand, France

  • CHU de Grenoble, Service de réanimation cardiovasculaire et thoracique, Pôle anesthésie réanimation, Hôpital Nord

    RECRUITING

    Grenoble, France

  • CHU de Montpellier, Département d'anesthésie-réanimation, Pôle Cœur-poumons, Hôpital Arnaud de Villeneuve

    RECRUITING

    Montpellier, France

  • CHU de Saint Etienne, Hôpital Bellevue, Service de Réanimation polyvalente et soins intensifs post-opératoires

    RECRUITING

    Saint-Etienne, France

  • Centre Hospitalo Universitaire de Dijon, Unité Réanimation Cardio-Vasculaire,

    RECRUITING

    Dijon, 21079, France

  • Centre Hospitalo Universitaire de Lille, Institut Coeur Poumon

    NOT_YET_RECRUITING

    Lille, 59037, France

  • Centre Hospitalo Universitaire de Toulouse, Hôpital Rangueil - Réanimation polyvalente

    NOT_YET_RECRUITING

    Toulouse, 31059, France

  • Centre Hospitalo Universitaire de Toulouse, Unité de Chirurgie Cardiaque

    NOT_YET_RECRUITING

    Toulouse, 31059, France

  • Hospices Civils de Lyon, Service d'Anesthésie-Réanimation cardiovasculaire, Hôpital Louis Pradel

    RECRUITING

    Lyon, France

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