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Can upright positioning help ARDS patients breathe easier?

NCT ID NCT04472260

Recruiting now Symptom relief Sponsor: Centre Hospitalier Régional d'Orléans Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether safely raising patients with acute respiratory distress syndrome (ARDS) to an upright position (verticalization) is feasible and safe. Researchers will compare upright positioning with standard prone positioning in 32 adults. The goal is to see if upright positioning can improve oxygen levels without causing serious side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Verticalization (upright positioning) and prone positioning procedures
What this could lead to
If successful, this could offer a safe alternative or addition to prone positioning for ARDS patients, potentially improving oxygen levels and reducing complications.
What could go wrong
This is a small, early feasibility study with only 32 participants, so results may not apply broadly. The procedure may not improve outcomes or could cause adverse events like pressure ulcers or tube issues.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME PRONE POSITION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHR d'ORLEANS

    RECRUITING

    Orléans, France

    Contact

    Contact

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