Could early norepinephrine save more septic shock patients?
NCT ID NCT07343206
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving the drug norepinephrine early and adjusting the dose quickly can improve survival in adults with septic shock. Researchers will compare this approach to standard care with a placebo. Six hundred participants will be monitored for 28 days to see if early treatment reduces deaths and speeds recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
norepinephrine
What this could lead to
If it works, this could establish a better way to treat septic shock, potentially saving more lives by stabilizing blood pressure faster.
What could go wrong
This is a single trial with 600 participants. Results may not apply to all patients, and norepinephrine can cause side effects like limb ischemia.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SEPSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Faculty of Medicine Siriraj Hospital, Mahidol University
RECRUITINGBangkok Noi, Bangkok, 10700, Thailand
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Hatyai Hospital
RECRUITINGHat Yai, Hat Yai, 90110, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Kalasin Hospital
RECRUITINGKalasin, Changwat Kalasin, 46000, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Khon Kaen hospital
RECRUITINGKhon Kaen, Changwat Khon Kaen, 4000, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Maharaj Nakhon Si Thammarat Hospital
RECRUITINGNakhon Si Thammarat, ์Nakhon Si Thammarat, 8000, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Udon Thani Hospital
RECRUITINGUdon Thani, Changwat Udon Thani, 41000, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact