E-Cig coolant study seeks the perfect chill
NCT ID NCT05932693
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed pilot study tested how different amounts of a coolant called WS-3 affect the sensation of e-cigarettes in 31 adult users. Participants tried various levels of WS-3 and rated the coolness, sweetness, and harshness. The goal was to find the right concentrations for future research.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- E-liquid coolant (WS-3)
- What this could lead to
- If successful, this study could help determine the right amount of coolant to use in e-cigarettes for a satisfying cooling sensation.
- What could go wrong
- This is a small, early pilot study with only 31 participants, so results may not apply to all e-cigarette users. It does not test health effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Yale School of Medicine
New Haven, Connecticut, 06473, United States
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