E-Cig coolant study seeks the perfect chill
NCT ID NCT05932693
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed pilot study tested how different amounts of a coolant called WS-3 affect the sensation of e-cigarettes in 31 adult users. Participants tried various levels of WS-3 and rated the coolness, sweetness, and harshness. The goal was to find the right concentrations for future research.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
E-liquid coolant (WS-3)
What this could lead to
If successful, this study could help determine the right amount of coolant to use in e-cigarettes for a satisfying cooling sensation.
What could go wrong
This is a small, early pilot study with only 31 participants, so results may not apply to all e-cigarette users. It does not test health effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Yale School of Medicine
New Haven, Connecticut, 06473, United States