New heart valve shows promise in early trial for aortic stenosis
NCT ID NCT05712161
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests a new device called the DurAVR™ heart valve in 15 people aged 65 and older with severe aortic stenosis, a condition where the heart's aortic valve becomes narrowed. The valve is implanted through a catheter (TAVR) without open-heart surgery. The main goals are to see if the procedure is safe and technically successful, measuring outcomes like death, stroke, and complications within 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DurAVR™ Transcatheter Heart Valve (THV) device
What this could lead to
If successful, this could provide a new, less invasive valve replacement option for people with severe aortic stenosis.
What could go wrong
This is a very early, small study (15 people) focused on safety and feasibility. The device may not work as well as existing valves, and risks include stroke, bleeding, or other complications.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Columbia University Medical Center/NYPH
New York, New York, 10032, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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Tucson Medical Center
Tucson, Arizona, 85712, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States