New trial combines HIV PrEP and STI prevention in one package for young men

NCT ID NCT07658976

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combined approach—offering HIV PrEP (pills or injections) and STI prevention (doxycycline after sex) along with smartphone tools—helps young men at high risk stay protected. About 400 men aged 18-29 who have sex with men will be followed for a year to see if the tools improve PrEP use and reduce infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HIV PrEP (F/TDF, F/TAF, or CAB-LA) and STI PEP (doxycycline)

What this could lead to

If successful, this approach could make it easier for young men to stick with HIV prevention and reduce sexually transmitted infections.

What could go wrong

This is a Phase 3 trial, but results depend on real-world adherence and may not apply to all populations. The mHealth tools may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS hepatitis B virus infection HIV infectious disease prevention target sexually transmitted disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bronx Prevention Research Center CRS

    The Bronx, New York, 10451, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundacion Huesped CRS

    Buenos Aires, C1427CEA, Argentina

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto de Pesquisa Clinicaq Evandro Chagas CRS

    Manguinhos, Rio de Janeiro, 221045-900, Brazil

  • San Miguel CRS

    Lima, 32-15088, Peru

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Vine Street Clinic

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••