Can a blood pressure drug help MSA patients stay steady on their feet?

NCT ID NCT02071459

First seen Apr 11, 2026 · Last updated Jun 02, 2026 · Updated 7 times

Summary

This study tested a drug called droxidopa (L-threo DOPS) against a placebo to see if it could reduce symptoms of orthostatic hypotension—dizziness and fainting when standing up—in people with multiple system atrophy (MSA). About 107 adults aged 30 to 80 with MSA and documented blood pressure drops took part. The main goal was to measure symptom changes after 12 weeks of treatment.

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Contacts and locations

Locations

  • CHRU de lille

    Lille, 59037, France

  • CHU Pontchaillou

    Rennes, 35033, France

  • CHU bordeaux

    Bordeaux, France

  • CHU de Clermont-Ferrand

    Clermont-Ferrand, 63000, France

  • CHU de Dijon

    Dijon, 21000, France

  • CHU de Poitiers

    Poitiers, 86021, France

  • CHU de Rouen

    Rouen, 76031, France

  • CHU de limoges

    Limoges, 87042, France

  • Centre hospitalier d'Angers

    Angers, 49933, France

  • Hôpital G. & R. Laennec

    Nantes, 44093, France

  • Hôpital La Timone

    Marseille, 13000, France

  • Hôpital Pitié-Salpétrière

    Paris, 75013, France

  • chu de Strasbourg

    Strasbourg, 67091, France

Conditions

Explore the condition pages connected to this study.