Computer model may help tailor blood pressure meds for liver patients
NCT ID NCT07397481
First seen Feb 19, 2026
Summary
This study tested whether a computer program (Simcyp) could predict the right doses of two blood pressure drugs, nebivolol and carvedilol, for people with liver cirrhosis and high blood pressure. Forty patients were randomly assigned to one of the two drugs and monitored for three months. Researchers measured blood pressure, liver blood flow, and side effects to see if the computer-guided doses worked well in real life.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Kafrelsheikh University
Cairo, Egypt, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nebivolol and carvedilol (blood pressure medications)
What this could lead to
If successful, this approach could help doctors choose safer, more effective doses of blood pressure drugs for patients with liver cirrhosis.
What could go wrong
This is a small, early pilot study with only 40 patients, so results may not apply to everyone. The computer predictions need more testing before routine use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.