Gentler chemo for seniors: DOROTHY trial aims to cut toxicity without sacrificing results
NCT ID NCT06042569
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times
Summary
This study is for women aged 65 and older with early-stage HER2-negative breast cancer. It tests whether a lower dose of the chemotherapy drugs docetaxel and cyclophosphamide can still be effective while causing fewer side effects and improving quality of life. About 174 participants will be enrolled to compare the standard dose with a reduced dose.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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