Breast milk from donors may help Antibiotic-Exposed Newborns' gut health

NCT ID NCT05815433

First seen Mar 03, 2026 · Last updated Jun 24, 2026 · Updated 20 times

Summary

This pilot study looked at whether giving donor human milk instead of formula to full-term babies whose mothers received antibiotics during labor could improve their gut bacteria and health. The study included 105 infants born vaginally at full term. Researchers compared the babies' gut microbiomes, sleep, growth, and their mothers' well-being between the two feeding groups.

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Contacts and locations

Locations

  • Rockyview General Hospital

    Calgary, Alberta, T2V 1P9, Canada

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

donor human milk

What this could lead to

If donor milk is shown to improve gut bacteria balance and health in antibiotic-exposed infants, it could support broader use of donor milk over formula for these babies.

What could go wrong

This is a small pilot study with only 105 participants, so results may not be conclusive. The study is completed but not yet published, and findings may not apply to all infants or settings.

Conditions

The condition(s) this trial relates to.

Breast Feeding infectious disease postpartum depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.