New PET scan probe could sharpen lung cancer detection

NCT ID NCT07508852

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new radioactive probe called PFD3, used with a PET/CT scan, to see if it can better find and assess small cell lung cancer (SCLC) by targeting a protein called DLL3 found on cancer cells. About 30 adults with SCLC will receive both a standard FDG scan and the new PFD3 scan to compare their accuracy. The goal is to improve diagnosis and monitoring of this aggressive cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

68Ga-PFD3 (a radioactive probe for PET/CT imaging)

What this could lead to

If successful, this could provide a more accurate way to diagnose and monitor small cell lung cancer, potentially guiding better treatment decisions.

What could go wrong

This is an early-phase trial with only 30 participants, so results may not apply to everyone. The probe's safety and effectiveness are still being tested.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disease small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking university first hospital nuclear medicine

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••