Blood test may help Fine-Tune breast cancer medication levels

NCT ID NCT06572800

Completed Knowledge-focused Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a blood test called DiviTum-TKa can help doctors check if patients with metastatic breast cancer are taking their CDK4/6 inhibitor medication correctly and if other drugs are interfering. The test measures a marker of cell growth to see if the treatment is working well. The goal was to see if adjusting medication based on test results could improve treatment response in 34 patients.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma Her2-receptor negative breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANATOMIC STAGE IV BREAST CANCER AJCC V8 METASTATIC HER2-NEGATIVE BREAST CARCINOMA

Contacts and locations

Locations

Smilow Cancer Center/Yale-New Haven Hospital

New Haven, Connecticut, 06510, United States
Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437, United States
Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385, United States
Smilow Cancer Hospital Care Center - Westerly

Westerly, Rhode Island, 02891, United States
Smilow Cancer Hospital Care Center at Glastonbury

Glastonbury, Connecticut, 06033, United States
Smilow Cancer Hospital Care Center at Greenwich

Greenwich, Connecticut, 06830, United States
Smilow Cancer Hospital Care Center at Long Ridge

Stamford, Connecticut, 06902, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
Smilow Cancer Hospital Care Center-Fairfield

Fairfield, Connecticut, 06824, United States
Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611, United States
Smilow Cancer Hospital-Derby Care Center

Derby, Connecticut, 06418, United States
Smilow Cancer Hospital-Hamden Care Center

Hamden, Connecticut, 06518, United States
Smilow Cancer Hospital-Orange Care Center

Orange, Connecticut, 06477, United States
Smilow Cancer Hospital-Torrington Care Center

Torrington, Connecticut, 06790, United States
Smilow Cancer Hospital-Waterbury Care Center

Waterbury, Connecticut, 06708, United States
Yale University

New Haven, Connecticut, 06520, United States
Yale-New Haven Hospital North Haven Medical Center

North Haven, Connecticut, 06473, United States
Yale-New Haven Hospital Saint Raphael Campus

New Haven, Connecticut, 06511, United States

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