Promising new combo therapy for tough childhood cancer
NCT ID NCT03786783
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times
Summary
This study tested whether adding two immunotherapy drugs (dinutuximab and GM-CSF) to standard chemotherapy is safe and feasible for children newly diagnosed with high-risk neuroblastoma, a rare and aggressive nerve cell cancer. About 42 children participated. The goal was to see if this combination could be given without causing too many severe side effects, while potentially helping the immune system fight the cancer more effectively.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15224, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032, United States
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Primary Children's Hospital
Salt Lake City, Utah, 84113, United States
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Royal Children's Hospital
Parkville, Victoria, 3052, Australia
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Saint Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Starship Children's Hospital
Grafton, Auckland, 1145, New Zealand
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The Children's Hospital at Westmead
Westmead, New South Wales, 2145, Australia
Conditions
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