Diet showdown: mediterranean fasting vs. Weight-Loss pill for fatty liver

NCT ID NCT06845345

First seen Dec 10, 2025 · Last updated May 23, 2026 · Updated 21 times

Summary

This study compares two ways to lose weight and reduce liver damage in people with cardiometabolic risks like type 2 diabetes or obesity. One group will follow a Mediterranean diet with intermittent fasting, while the other group takes a weight-loss medication (naltrexone/bupropion). The goal is to see which approach better reduces liver scarring (fibrosis) over six months. About 70 adults with moderate liver scarring will participate.

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Contacts and locations

Locations

  • Franciscus

    Rotterdam, 3045 PM, Netherlands

Conditions

Explore the condition pages connected to this study.