Can a better diet ease MS symptoms? new study tests diet quality and calorie cutting

NCT ID NCT05327322

Ongoing Symptom relief Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether improving diet quality and reducing calories can help physical function, thinking, pain, fatigue, mood, and anxiety in 100 adults with relapsing-remitting or secondary progressive multiple sclerosis. Participants receive prepared meals and behavioral support over 32 weeks. The goal is to see if these dietary changes can ease MS symptoms and improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dietary intervention (glycemic load and calorie restriction)
What this could lead to: If successful, this could point toward a simple dietary approach to help manage symptoms like fatigue, pain, and mobility issues in multiple sclerosis.
What could go wrong: This is a relatively small, early-stage study (100 participants) testing behavioral changes, not a drug. Results may not apply to all MS patients, and dietary adherence can be challenging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic progressive multiple sclerosis relapsing-remitting multiple sclerosis secondary progressive multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RELAPSING-REMITTING MULTIPLE SCLEROSIS SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS

Contacts and locations

Locations

University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
Washington University

St Louis, Missouri, 63110, United States

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