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Which painkiller works best after a root canal? study pits diclofenac against ibuprofen

NCT ID NCT07565012

Completed Symptom relief Sponsor: Armed Forces Institute of Dentistry, Pakistan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two common painkillers—diclofenac sodium and ibuprofen—for managing pain after a root canal. Sixty adults with irreversible pulpitis received one of the two drugs right after treatment, and their pain was tracked for 48 hours. The goal was to see which drug provides better relief and reduces the need for extra pain medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
diclofenac sodium and ibuprofen
What this could lead to
If successful, this study could help dentists choose the most effective painkiller for post-root canal pain, improving patient comfort.
What could go wrong
This is a small, completed Phase 4 trial with only 60 participants, so results may not apply to everyone. Both drugs are well-known, so no major surprises are expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRREVERSIBLE PULPITIS POST ENDODONTIC PAIN ROOT CANAL TREATMENT

Contacts and locations

Locations

  • Armed Forces Institute of Dentistry

    Rawalpindi, 46000, Pakistan

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