Study aims to improve ventilator weaning by measuring diaphragm strength

NCT ID NCT07206459

Ongoing Knowledge-focused Sponsor: Unity Health Toronto Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study looks at how the amount of air left in the lungs after breathing out affects measurements of diaphragm strength. Researchers will test 30 healthy volunteers and then compare results with ventilated ICU patients. The goal is to develop a way to correct diaphragm strength readings based on lung volume, which could help doctors make better decisions about removing patients from ventilators.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a method to correct diaphragm strength measurements in ventilated patients, potentially improving decisions about weaning them off ventilators.
What could go wrong: This is a small, early-stage observational study in healthy volunteers and a limited number of patients. The findings may not apply to all ICU patients or lead to direct clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION

Contacts and locations

Locations

St. Michael's Hospital

Toronto, Ontario, Canada

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