Nasal spray may curb Post-Surgery confusion in seniors
NCT ID NCT07579806
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a nasal spray containing dexmedetomidine can reduce the chance of postoperative delirium (sudden confusion) in people 65 and older after lung surgery. About 264 participants will be randomly assigned to get either the drug or a placebo spray before surgery. Researchers will track confusion, pain, sleep quality, and side effects for three days after the operation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine hydrochloride nasal spray
What this could lead to
If it works, this could offer a simple, non-invasive way to lower the risk of confusion after lung surgery in older adults.
What could go wrong
This is a single, mid-sized trial. The effect may be small or not better than placebo, and side effects like low blood pressure or slow heart rate are possible.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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