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Could a simple blood pressure target during surgery prevent delirium in older patients?

NCT ID NCT07713121

Not yet recruiting Disease control Sponsor: Universitätsklinikum Hamburg-Eppendorf Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial investigates whether maintaining a higher blood pressure (85 mmHg or above) during surgery can reduce the risk of postoperative delirium—a sudden confusion that can occur after surgery—in older adults (65+) with high blood pressure. About 3,400 participants having non-cardiac surgery will be randomly assigned to either a higher or standard blood pressure target. The goal is to see if this simple adjustment can prevent delirium and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
targeted blood pressure management (maintaining mean arterial pressure at 85 mmHg or higher during surgery)
What this could lead to
If successful, this approach could provide a simple, low-cost way to prevent postoperative delirium in older adults with high blood pressure.
What could go wrong
This is a single trial, and previous smaller studies have shown mixed results. The intervention may not reduce delirium or could increase risks from overtreatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRAOPERATIVE HYPOTENSION POSTOPERATIVE DELIRIUM (POD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • • Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg

    Hamburg, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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