Gene test may help pick the right meds for pain and depression

NCT ID NCT04445792

First seen Apr 04, 2026 · Last updated May 01, 2026 · Updated 2 times

Summary

This study looked at whether genetic testing can help doctors choose safer and more effective medicines for depression, acute pain, and chronic pain. Over 4,200 people took part. Some got genetic testing right away to guide their treatment, while others got standard care. The goal was to see if the genetic approach leads to better pain control or fewer depression symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Eskenazi Health

    Indianapolis, Indiana, 46202, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Meharry Medical College

    Nashville, Tennessee, 37208, United States

  • Nashville General Hospital

    Nashville, Tennessee, 37208, United States

  • Nemours Children's Health System

    Wilmington, Delaware, 19803, United States

  • Nemours Children's Health System

    Jacksonville, Florida, 32207, United States

  • Nemours Children's Health System

    Orlando, Florida, 32827, United States

  • Sanford Health

    Fargo, North Dakota, 58104, United States

  • The Institute for Family Health

    New York, New York, 10035, United States

  • University of Florida - Gainesville

    Gainesville, Florida, 32610, United States

  • University of Florida - Jacksonville

    Jacksonville, Florida, 32209, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.