Can better training help HIV patients beat depression?

NCT ID NCT07032363

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two sets of strategies to help HIV clinics in Cape Town, South Africa, treat depression and improve medication adherence. Ten clinics will be randomly assigned to receive either basic support or enhanced training and supervision. Researchers will track how many patients start depression treatment and whether their depression and HIV viral levels improve over a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show which training and support methods best help clinics treat depression in people with HIV, potentially improving health for many patients.

What could go wrong

This is a small, early-stage implementation study with only 10 clinics, so results may not apply to other settings. It tests strategies, not a new drug, so direct patient benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS Depression depressive disorder HIV infectious disease Treatment Adherence and Compliance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • University of Cape Town

    RECRUITING

    Cape Town, South Africa

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••