Steering brain stimulation could ease Parkinson's symptoms

NCT ID NCT03548506

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two types of deep brain stimulation in 20 people with Parkinson's disease: standard omnidirectional stimulation and a newer directional steering method. The goal was to see if steering the stimulation could better control motor symptoms like muscle rigidity. Participants received both types in a randomized, double-blind crossover design, and the researchers measured effects using muscle activity and clinical rating scales.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Deep brain stimulation device
What this could lead to
If successful, this could lead to more precise deep brain stimulation that better controls Parkinson's motor symptoms with fewer side effects.
What could go wrong
This is a small, early-stage study with only 20 participants, so results may not apply to all Parkinson's patients. The benefits of directional stimulation over standard stimulation are still uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Tuebingen, Dep. of Neurosurgery (Functional Neurosurgery) and Neurology (Neurodegenerative Diseases)

    Tübingen, Baden-Wurttemberg, 72076, Germany

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