Brain tumor clues: can MRI and a protein guide treatment?

NCT ID NCT06090903

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at whether MRI scans and a protein called decorin can help identify which glioblastoma patients might benefit from a drug called bevacizumab. Researchers will collect tissue samples from 50 patients during surgery and compare them with MRI images. The goal is to find imaging markers that predict treatment response, not to test a new therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which glioblastoma patients will respond to bevacizumab, potentially personalizing treatment and saving costs.
What could go wrong
This is an early observational study with only 50 participants, so results may not apply to all patients. It does not test a new treatment directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UCLA / Jonsson Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90095, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.