Brain pacemaker tested for dystonia relief

NCT ID NCT02686125

First seen Jun 26, 2026 · Last updated Aug 07, 2026 · Updated 7 times

Summary

This study is tracking how well the VERCISE™ deep brain stimulation (DBS) system works for people with dystonia, a movement disorder causing muscle spasms. Researchers will follow 300 participants aged 7 and older who are already receiving DBS to see if their symptoms improve. The goal is to gather real-world evidence on the device's effectiveness and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
deep brain stimulation (DBS) device
What this could lead to
If successful, this could confirm that DBS with the VERCISE™ system is a safe and effective way to reduce dystonia symptoms in everyday medical practice.
What could go wrong
This is an observational registry, not a controlled trial, so results may be less definitive. DBS involves brain surgery, which carries risks like infection or bleeding.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • 10 Military Clinical Hospital Bydgoszcz

    TERMINATED

    Bydgoszcz, Poland

  • AZ Sint-Lucas

    TERMINATED

    Ghent, Belgium

  • Azienda Ospedaliero-Universitaria di Ferrara

    COMPLETED

    Ferrara, Italy

  • Centro Especial Ramon y Cajal

    COMPLETED

    Madrid, Spain

  • Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie

    TERMINATED

    Warsaw, Poland

  • Charing Cross Hospital

    RECRUITING

    London, United Kingdom

  • Evangelisches Krankenhaus Oldenburg

    WITHDRAWN

    Oldenburg, Germany

  • Hadassah Hebrew University Medical Center

    COMPLETED

    Jerusalem, Israel

  • Haga Ziekenhuis locatie Leyweg

    RECRUITING

    The Hague, Netherlands

  • Hospital Clinic de Barcelona

    COMPLETED

    Barcelona, Spain

  • Hospital General De Asturias

    WITHDRAWN

    Oviedo, Spain

  • Johannes Gutenberg Universitaet Mainz

    TERMINATED

    Mainz, Germany

  • Medical School of University PECS

    RECRUITING

    Pécs, Hungary

  • Medizinische Hochschule Hannover MHH

    RECRUITING

    Hanover, Germany

  • National Scientific Center of Neurosurgery N.N. Burdenko

    TERMINATED

    Moscow, Russia

  • Osp. S. Maria Della Misericordia

    TERMINATED

    Udine, Italy

  • Ospedale Dell Angelo

    RECRUITING

    Mestre, Italy

  • Podmiot Leczniczy Copernicus Sp. z o.o.

    TERMINATED

    Gdansk, Poland

  • Policlinico Universitario Agostino Gemelli

    COMPLETED

    Rome, Italy

  • Queen Elizabeth II Health Sciences Center

    RECRUITING

    Halifax, Canada

  • Queen Elizabeth University Hospital

    COMPLETED

    Glasgow, United Kingdom

  • Royal Victoria Infirmary

    RECRUITING

    Newcastle upon Tyne, United Kingdom

  • Southmead Hospital Bristol

    WITHDRAWN

    Bristol, United Kingdom

  • St. Barbara-Klinik Hamm-Heessen

    COMPLETED

    Hamm, Germany

  • St. Mary's Hospital Incheon

    ACTIVE_NOT_RECRUITING

    Incheon, South Korea

  • UZ Gasthuisberg

    RECRUITING

    Leuven, Belgium

  • Uniklinik Köln

    RECRUITING

    Cologne, Germany

  • Universitaetsklinik Eppendorf

    RECRUITING

    Hamburg, Germany

  • Universitaetsklinikum Dusseldorf

    RECRUITING

    Düsseldorf, Germany

  • Universitaetsklinikum Freiburg

    RECRUITING

    Freiburg im Breisgau, Germany

  • Universitaetsklinikum Giessen und Marburg GmbH

    RECRUITING

    Marburg, Germany

  • Universitaetsklinikum Wuerzburg

    RECRUITING

    Würzburg, Germany

  • Universitatsklinikum Campus Kiel

    RECRUITING

    Kiel, Germany

  • University Berlin, Charite Virchow Standort, Wedding

    RECRUITING

    Berlin, Germany

  • University Hospital Virgen Arrixaca

    WITHDRAWN

    El Palmar, Spain

  • Wojewodzki Szpital Dzieciecy Jozefa Brudzinskiego (Childrens Hospital Bydgoszcz)

    TERMINATED

    Bydgoszcz, Poland

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