New drug combo may boost prostate cancer surgery success

NCT ID NCT05826509

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the drug darolutamide before and after surgery helps men with high-risk or locally advanced prostate cancer. About 240 men will either have surgery alone or surgery plus the drug. The goal is to see if the drug delays the cancer from coming back or spreading.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Bordeaux

    Bordeaux, France

  • CHU Grenoble

    Grenoble, France

  • CHU Lyon - Hôpital Edouard Herriot

    Lyon, France

  • CHU Lyon - Sud

    Pierre-Bénite, France

  • CHU Rennes

    Rennes, France

  • CHU Toulouse

    Toulouse, France

  • Chu Angers

    Angers, France

  • Chu Henri Mondor

    Créteil, France

  • Chu Tours - Hopital Bretonneau

    Tours, France

  • Clinique La Croix Du Sud

    Quint-Fonsegrives, France

  • Hopital Claude Huriez

    Lille, France

  • Hopital Europeen Georges-Pompidou

    Paris, France

  • Hopital Foch

    Suresnes, France

  • Hopital Paris Saint-Joseph

    Paris, 75014, France

  • Hopital Pitie Salpetriere

    Paris, France

  • Institut Bergonié

    Bordeaux, France

  • Institut Mutualiste Montsouris

    Paris, France

  • Institut Paoli-Calmettes

    Marseille, France

  • Institut Universitaire Du Cancer Toulouse - Oncopole

    Toulouse, France