Could a common blood thinner help fight staph infections?

NCT ID NCT06650501

Recruiting now Disease control Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether switching to the blood thinner dabigatran can improve outcomes for people with a serious staph bloodstream infection who are already taking other blood thinners. Researchers will compare those who switch to dabigatran with those who stay on their current medication. The goal is to see if dabigatran reduces complications and death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dabigatran
What this could lead to: If successful, this could point to a way to improve survival and reduce complications in patients with serious staph bloodstream infections who already need blood thinners.
What could go wrong: This is a relatively small, early-phase trial, and the benefit seen in lab tests may not translate to real-world patients. There is also a risk of bleeding or other side effects from changing blood thinners.

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Conditions

The condition(s) this trial relates to.

bacterial endocarditis bacterial infectious disease with sepsis staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

S. AUREUS BACTEREMIA S. AUREUS BLOODSTREAM INFECTION STAPHYLOCOCCUS AUREUS BACTEREMIA STAPHYLOCOCCUS AUREUS BLOODSTREAM INFECTION STAPHYLOCOCCUS AUREUS ENDOCARDITIS STAPHYLOCOCCUS AUREUS SEPTICEMIA

Contacts and locations

Locations

McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital)
RECRUITING

Montreal, Quebec, H4A3S1, Canada

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