Blood test may spare thousands from unnecessary cancer surgery

NCT ID NCT06040632

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a blood test that detects tumor DNA can accurately identify patients who still have cancer after local removal of early-stage colorectal cancer. Currently, many patients undergo additional surgery even though about 85% are already cured by the initial procedure. If the blood test works, it could help doctors decide who truly needs more surgery and who can safely avoid it. The study involves 67 participants in Denmark.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

circulating tumor DNA (ctDNA) blood test

What this could lead to

If accurate, this blood test could help many patients avoid unnecessary follow-up surgery after early colorectal cancer removal.

What could go wrong

This is a small observational study (67 people) in Denmark, so results may not apply broadly. The test may not reliably detect all residual cancers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal carcinoma colorectal neoplasm polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aalborg University Hospital

    Aalborg, North Denmark, 9000, Denmark

  • Aarhus University Hospital

    Aarhus, Central Jutland, 8000, Denmark

  • Bispebjerg Hospital

    Copenhagen, Capital Region of Denmark, 2400, Denmark

  • Gødstrup Hospital

    Herning, Central Jutland, 7400, Denmark

  • Herlev Hospital

    Herlev, Capital Region of Denmark, 2730, Denmark

  • Odense University Hospital

    Odense, The Region of Southern Denmark, 5000, Denmark

  • Regional Hospital Horsens

    Horsens, Central Jutland, 8700, Denmark

  • Regional Hospital Randers

    Randers, Central Jutland, 8930, Denmark

  • Regional Hospital Viborg

    Viborg, Central Jutland, 8800, Denmark