Freezing nerves to stop rib pain: a new hope?
NCT ID NCT05865327
First seen Oct 01, 2025 · Last updated Jun 22, 2026 · Updated 29 times
Summary
This small pilot study tests whether freezing the nerves around broken ribs can reduce pain. Participants will receive either the freezing procedure or a sham treatment, along with standard pain care. The goal is to see if a larger trial is possible and to measure pain levels and medication use over 3 months.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N3M5, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryoneurolysis (nerve freezing procedure)
What this could lead to
If it works, this could lead to a new way to manage severe rib fracture pain and reduce long-term complications.
What could go wrong
This is a very small pilot study (24 people) testing feasibility, not effectiveness. The procedure may not provide better pain relief than standard care, and there is a risk of nerve damage or side effects from freezing.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.