Heart device tweak aims to help Non-Responders

NCT ID NCT04763460

Terminated Knowledge-focused Sponsor: Minneapolis Heart Institute Foundation Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study planned to test a new way to program cardiac resynchronization therapy (CRT) devices for heart failure patients who didn't get enough benefit from standard settings. Researchers would use ECG and cardiac MRI to find the best device settings and measure changes in heart function. However, the study was withdrawn before any participants were enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CRT device programming optimization
What this could lead to: If successful, this could lead to better ways to program CRT devices for heart failure patients who don't respond to standard settings.
What could go wrong: The study was withdrawn before enrolling any participants, so no results are available. It's unclear if the approach would work in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE, SYSTOLIC

Contacts and locations

Locations

Minneapolis Heart Institute - Abbott Northwestern Hospital (MHI West)

Minneapolis, Minnesota, 55407, United States
United Heart & Vascular Clinic - Nasseff Specialty Center (MHI East)

Saint Paul, Minnesota, 55102, United States

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