Creatine: a new weapon against Post-Surgery brain fog?

NCT ID NCT07310043

First seen Jun 24, 2026 · Last updated Aug 11, 2026 · Updated 5 times

Summary

This study tests whether taking creatine supplements before surgery can help protect thinking, memory, and attention in older adults. Creatine is widely used for muscle performance, but may also support brain health. Researchers will give creatine to 80 older adults scheduled for elective surgery and measure their cognitive function and delirium risk afterward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
creatine monohydrate
What this could lead to
If it works, this could point toward a simple, low-cost way to help older adults avoid confusion and memory problems after surgery.
What could go wrong
This is a small, early-stage study with only 80 people. Creatine is generally safe, but it's not proven to help brain function after surgery, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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