Creatine: a new weapon against Post-Surgery brain fog?

NCT ID NCT07310043

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking creatine supplements before surgery can help protect thinking, memory, and attention in older adults. Creatine is widely used for muscle performance, but may also support brain health. Researchers will give creatine to 80 older adults scheduled for elective surgery and measure their cognitive function and delirium risk afterward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

creatine monohydrate

What this could lead to

If it works, this could point toward a simple, low-cost way to help older adults avoid confusion and memory problems after surgery.

What could go wrong

This is a small, early-stage study with only 80 people. Creatine is generally safe, but it's not proven to help brain function after surgery, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.