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New drug aims to tame rare, Exercise-Triggered heart condition

NCT ID NCT06658899

Recruiting now Disease control Sponsor: Cardurion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study tests an experimental drug called CRD-4730 in 12 adults with a rare inherited heart condition (CPVT) that can cause dangerous heart rhythms during exercise or stress. Participants will receive two different doses of the drug and a placebo in random order to see if it safely reduces abnormal heartbeats. The goal is to better control the condition, not cure it.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac catecholaminergic polymorphic ventricular tachycardia Polymorphic Catecholaminergic Ventricular Tachycardia ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Cardurion Investigative Site

    RECRUITING

    San Francisco, California, 94143, United States

  • Cardurion Investigative Site

    RECRUITING

    Morrisville, North Carolina, 27560, United States

  • Cardurion Investigative Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Cardurion Investigative Site

    RECRUITING

    Salt Lake City, Utah, 84113, United States

  • Cardurion Investigative Site

    RECRUITING

    Madison, Wisconsin, 53792, United States

  • Cardurion Investigative Site

    RECRUITING

    Vancouver, British Columbia, V6Z 1Y6, Canada

  • Cardurion Investigative Site

    RECRUITING

    Bron, 69677, France

  • Cardurion Investigative Site

    RECRUITING

    Paris, 75018, France

  • Cardurion Investigative Site

    RECRUITING

    Saint-Herblain, 44800, France

  • Cardurion Investigative Site

    RECRUITING

    Pavia, Pavia, 27100, Italy

  • Cardurion Investigative Site

    RECRUITING

    Amsterdam, North Holland, 1105 AZ, Netherlands

  • Cardurion Investigative Site

    RECRUITING

    Esplugues de Llobregat, Barcelona, 08950, Spain

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