TB Patients' COVID-19 vaccine response under the microscope
NCT ID NCT05571735
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares the immune response to COVID-19 vaccines between people being treated for tuberculosis (TB) and healthy individuals. About 133 participants in the Thailand-Myanmar border area will receive one of three vaccines (Pfizer, AstraZeneca, or Janssen). Researchers will measure antibody and cell-based immunity over one year to see if TB treatment affects vaccine effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
COVID-19 vaccines (Pfizer-BioNTech, AstraZeneca, or Janssen)
What this could lead to
If successful, this could show that TB patients mount a similar immune response to COVID-19 vaccines as healthy people, helping guide vaccination policies for this group.
What could go wrong
This is a small observational study, not a large trial. Results may not apply to all TB patients or other settings, and immune response does not guarantee protection from COVID-19.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shoklo Malaria Research Unit (SMRU)
RECRUITINGMae Ramat, Changwat Tak, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••