Which CLL drug gives best bang for the buck? new study analyzes costs and patient Well-Being

NCT ID NCT02414022

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study looks at the cost-effectiveness of three treatments for chronic lymphocytic leukemia (CLL) in patients aged 65 and older. Researchers compared ibrutinib alone or with rituximab against bendamustine plus rituximab, measuring both healthcare costs and quality of life. The goal is to help public health systems decide which treatment offers the best value.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ibrutinib, rituximab, bendamustine

What this could lead to

If successful, this could help healthcare systems decide which treatment offers the best value for money in older CLL patients.

What could go wrong

This is an economic analysis of a small subset of patients, not a new treatment trial. Results may not apply to all patients or healthcare settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Allan Blair Cancer Centre

    Regina, Saskatchewan, Canada

  • CHUM-CEntre Hospitalier de l'Universite de Montreal

    Montreal, Quebec, Canada

  • CSSS Champlain-Charles LeMoyne

    Greenfield Park, Quebec, Canada

  • Health Sciences North

    Greater Sudbury, Ontario, Canada

  • Humber River Hospital

    Toronto, Ontario, Canada

  • Juravinski Cancer Centre at Hamilton Health Sciences

    Hamilton, Ontario, Canada

  • Kingston Health Sciences Centre

    Kingston, Ontario, K7L3N6, Canada

  • London Regional Cancer Program

    London, Ontario, Canada

  • Odette Cancer Centre Sunnybrook Health Sciences Centre

    Toronto, Ontario, Canada

  • Ottawa Hospital Research Institute

    Ottawa, Ontario, Canada

  • Stronach Regional Health Centre at Southlake

    Newmarket, Ontario, L3Y 2P9, Canada

  • The Jewish General Hospital

    Montreal, Quebec, Canada

  • The Moncton Hospital

    Moncton, New Brunswick, Canada

  • Tom Baker Cancer Centre

    Calgary, Alberta, Canada

  • University Health Network Princess Margaret Cancer Centre

    Toronto, Ontario, Canada