Dialysis blood pressure mystery: could a simple blood test hold clues?
NCT ID NCT07438925
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is investigating whether a substance called copeptin, which is a stable marker of the hormone vasopressin, is linked to blood pressure changes that happen during hemodialysis. Researchers will measure copeptin levels in routine blood samples from 71 adults on chronic dialysis and compare them with blood pressure readings taken before, during, and after sessions. The goal is to better understand how the body regulates fluid and blood pressure during dialysis, which could eventually help improve patient care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand blood pressure swings during dialysis, potentially leading to improved monitoring or treatment strategies.
- What could go wrong
- This is a small, observational study (71 people) that only looks for a link, not a treatment. The results may not apply to all dialysis patients or lead to any direct changes in care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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71 people
The number who actually took part.
- Started
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Dec 2025
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult patients (≥18 years old) undergoing chronic hemodialysis for more than three months. All included patients were clinically stable, not hospitalized at the time of data collection, and received treatment within the ALTIR network (Association Lorraine pour le Traitement de l'Insuffisance Rénale). Data were obtained from three hemodialysis centers: Nancy-Brabois, Champelle, and Épinal.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (≥18 years old). * Undergoing chronic hemodialysis treatment \> 3 months. * Availability of routine predialysis blood samples for copeptin and biochemical measurements. * Availability of blood pressure recordings before, during, and after hemodialysis sessions. No exclusion criteria if inclusion criteria is filled
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHRU de Nancy
Vandœuvre-lès-Nancy, 54500, France
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