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Can light therapy speed up dialysis fistula healing?

NCT ID NCT07787195

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether low-level laser therapy or isometric handgrip exercises can help arteriovenous fistulas mature faster in people on hemodialysis. A fistula is a surgically created connection between an artery and vein that needs to grow and widen before it can be used for dialysis. The study will compare laser sessions, handgrip exercises, and standard care in 75 adults with chronic kidney disease who have a new fistula, measuring vein diameter, blood flow, and overall maturation after eight weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low-level laser therapy and isometric handgrip exercise
What this could lead to
If effective, this could offer a non-invasive way to help dialysis fistulas mature faster, reducing the need for catheters and improving dialysis access.
What could go wrong
This is a small, early-stage trial, and results may not apply to all patients. Laser therapy and exercise may not improve fistula maturation, and there are potential risks like skin irritation or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients of both genders. * Patient age between 35 and 50 years. * Diagnosed with chronic kidney disease (CKD) Stage 4 or 5 with a newly created radiocephalic arteriovenous fistula (RC-AVF), including both pre-dialysis patients and those temporarily receiving hemodialysis via central venous catheter pending fistula maturation. * Distal forearm cephalic vein diameter ≥ 2.5 mm in the non-dominant hand Exclusion Criteria: * History of prior vascular access surgery on the same limb. * Physical or mental disability limiting the ability to perform exercises. * Positive Allen's test. * Absent or thrombosed distal forearm cephalic vein. * Already undergoing regular exercise (including manual workers). * History of hemophilia or known coagulation disorder. * Personal or family history of cancer. * Severe cardiac disease (congestive heart failure with ejection fraction ≤ 20%). * Known central venous stenosis \> 50% on the side of planned arteriovenous fistula creation.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodialysis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cairo university

    Cairo, Egypt

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