COPD immune mystery: scientists probe why lungs can't clear bacteria.

NCT ID NCT05743582

Recruiting now Knowledge-focused Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why immune cells in people with COPD don't work properly to clear bacteria from the lungs. Researchers will collect cells from the lungs and blood of 189 participants, including COPD patients and healthy smokers and non-smokers. They will study how these cells use energy and respond to bacteria, aiming to find new ways to treat COPD in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new treatments for COPD by targeting immune cell metabolism.
What could go wrong: This is an observational study, not a treatment trial. It is early-stage research, and findings may not lead to therapies for years, if at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Contacts and locations

Locations

Royal Infirmary of Edinburgh
RECRUITING

Edinburgh, EH16 5SA, United Kingdom
University of Edinburgh
NOT_YET_RECRUITING

Edinburgh, EH16 4TJ, United Kingdom

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