New pain block after kidney stone surgery could cut opioid use

NCT ID NCT05121168

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a continuous nerve block (using the numbing medicine bupivacaine) can reduce pain and opioid use after kidney stone surgery. Fifty adults having surgery received a single nerve block plus a catheter, then were randomly given either more numbing medicine or a placebo (salt water) for two days. The goal was to see if the continuous block improves pain scores and lowers opioid consumption compared to a single injection alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine

What this could lead to

If it works, this could offer a better way to manage pain after kidney stone surgery, reducing the need for opioids.

What could go wrong

This is a small, completed Phase 4 trial with only 50 participants. The benefit over a single injection may be small, and the catheter can cause discomfort or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UC San Diego

    San Diego, California, 92103, United States

  • University of California, San Diego

    San Diego, California, 92103, United States