Brain zap tailored to each patient could tame tough OCD
NCT ID NCT05160129
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a personalized version of deep brain stimulation (DBS) for people with severe obsessive-compulsive disorder (OCD) that hasn't improved with other treatments. Researchers will adjust the stimulation to target specific brain circuits linked to each patient's symptoms. The goal is to see if this tailored approach works better than standard DBS, which already helps about 60% of patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deep brain stimulation device
What this could lead to
If successful, this could make DBS more effective for severe OCD by tailoring stimulation to each patient's brain connections.
What could go wrong
This is a small early-stage study (22 people) testing a new approach, so results may not apply broadly. DBS also carries surgical risks like infection or bleeding.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Mount Sinai West
RECRUITINGNew York, New York, 10019, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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