Which IV drug eases concussion symptoms best? new trial aims to find out

NCT ID NCT07634393

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two intravenous medications—metoclopramide and acetaminophen—to see which one better relieves acute concussion symptoms like headache, dizziness, and nausea in emergency room patients. Researchers will enroll 200 adults with mild head injuries and track their symptoms over a week. The goal is to provide clearer guidance on which drug works best for post-concussion care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

metoclopramide and acetaminophen

What this could lead to

If it works, this could point toward a better standard treatment for concussion symptoms in the emergency room.

What could go wrong

This is a small, early-phase trial with only 200 participants, so results may not apply to everyone. Both drugs are already used, so no major new risks are expected, but the study may not find a clear winner.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Concussion Craniocerebral Trauma head injury Post-Concussion Syndrome traumatic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Montefiore Medical Center

    New York, New York, 10467, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••