Concussion headache drug trial halted early — no clear answers yet
NCT ID NCT04226365
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 25 times
Summary
This study tested whether the drug nortriptyline could help teenagers with headaches after a concussion. Participants were randomly assigned to receive either the drug or a placebo for 4 weeks. The trial was stopped early and only enrolled 8 people, so it is not known if nortriptyline works better than a placebo for this condition.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Penn Medicine Lancaster General Health
Lancaster, Pennsylvania, 17602, United States
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