Heart procedure showdown: which ablation system sends fewer clots to the brain?
NCT ID NCT07610018
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will compare five different pulsed field ablation systems used to treat atrial fibrillation (an irregular heartbeat). The goal is to see which system causes the fewest tiny clots (microemboli) that travel to the brain during the procedure. One hundred adults with atrial fibrillation will be randomly assigned to one of the systems, and a special ultrasound will measure brain clots before and after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pulsed field ablation systems (PulseSelect, Varipulse, Farapulse, Sphere-9, Sphere-360)
What this could lead to
If one system causes fewer microemboli, it may become the preferred choice for safer atrial fibrillation ablation.
What could go wrong
This is an early-stage, small study (100 participants) that only measures a surrogate marker (microemboli), not actual stroke risk. Results may not change practice.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UH Dubrava
Zagreb, 10000, Croatia
Contact
Contact
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University Hospital Center Sisters of Charity, Zagreb, Croatia
Zagreb, 10000, Croatia